High-Density Lipoprotein (HDL) Cholesterol

Introduction

Cholesterol carried by HDL is considered “good” cholesterol. HDL collects cholesterol from around the body, and delivers it to the liver for recycling or excretion. HDL also carries cholesterol to other organs, where it is used to produce hormones. Low HDL cholesterol levels increase the risk of heart disease, independent of other risk factors associated with heart disease.

Pricing

$49

How to order a test

Synonyms

• HDL Cholesterol
• HDLC

What is Included?

Measurement of high-density lipoprotein (HDL) cholesterol levels in a blood sample by accelerator selective detergent methodology.

Turnaround Time

1 – 3 business days
The turnaround time is not guaranteed. The average turnaround time is 1 – 3 business days from the date that the sample arrives at the laboratory. Shipping time for the sample is not included. Additional time is required if the case requires confirmatory or reflex testing, or if the sample is insufficient, or if a recollection is required.

Related Documents

Additional Information and Resources

» “Bad” versus “good” cholesterol
» What are the risk factors for heart disease?
» What are the signs and symptoms of atherosclerosis?
» How to keep a healthy heart
» Cholesterol levels in common foods ​
» There are such things as good fats! ​

Preparation Before Specimen Collection

• Follow a normal diet for a week prior to specimen collection.
• Avoid taking any drugs for 3–4 weeks prior to specimen collection if possible.
• No fasting is necessary.

Specimen Type

Blood

Volume

50 μL in a microtainer

Container

Microtainer (regular blood tube)

Collection Method

This test requires a blood sample from a finger prick. All supplies for sample collection are provided in the kit.

1. First wash and dry hands. Warm hands aid in blood collection.
2. Clean the finger prick site with the alcohol swab and allow to air dry.
3. Use the provided lancet to puncture the skin in one quick, continuous and deliberate stroke.
4. Wipe away the first drop of blood.
5. Massage hand and finger to increase blood flow to the puncture site. Angle arm and hand downwards to facilitate blood collection on the fingertip.
6. Drip blood into the microtainer tube.
7. Dispose of all sharps safely and return sample to the laboratory in the provided prepaid return shipping envelope.

NOTES: Avoid squeezing or ‘milking’ the finger excessively. If more blood is required and blood flow stops, perform a second skin puncture on another finger. Do not touch the fingertip.

Specimen Storage

Maintain specimen at temperatures between 2°C and 30°C during storage and transport.

Specimen Stability

Blood samples can be refrigerated or kept at room temperature for up to 7 days.

Causes for Rejection

• Incorrect or incomplete patient identification
• Incorrect specimen collection
• Inappropriate storage and transport conditions
• Incorrect specimen volume

Purpose

To measure HDL cholesterol levels in a blood sample for the evaluation of cardiac health and the risk of coronary heart disease.

Limitations

• This report is not intended for use in medico-legal applications. 
• These results should be interpreted in conjunction with other laboratory and clinical information.
• Correct specimen collection and handling is required for optimal assay performance. 
• Interferences from medication or endogenous substances may affect results.
• Abnormal liver function can affect lipid metabolism and HDL cholesterol levels.
• Elevated concentrations of N-acetyl-L-cysteine may lead to falsely low HDL levels in this assay.

Methodology

Accelerator selective detergent (Alinity c Ultra HDL assay)

Reference Intervals

These reference ranges were obtained from the Alinity c Ultra HDL package insert, which follow recommendations from the National Cholesterol Education Program (NCEP) Adult Treatment Panel III Report.