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Iron

Test ID: A883

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Introduction

Measurement of iron levels in blood are useful for the evaluation of iron status, including red blood cell production and destruction, iron metabolism, and iron transport. Increased iron concentrations occur in haemolytic anemias, hemochromatosis, and acute liver disease. Decreased iron concentrations are seen in iron deficiency and anemia of chronic disease, with major causes of iron deficiency including gastrointestinal bleeding and menstrual bleeding.

Pricing

$49

How to order a test

Synonyms

  • Fe
  • Total Iron

What is Included?

Measurement of iron levels in a blood sample by colorimetric (ferene) methodology.

Turnaround Time

1 – 3 business days
The turnaround time is not guaranteed. The average turnaround time is 1 – 3 business days from the date that the sample arrives at the laboratory. Shipping time for the sample is not included. Additional time is required if the case requires confirmatory or reflex testing, or if the sample is insufficient, or if a recollection is required.

Related Documents

Additional Information and Resources

SPECIMEN REQUIREMENTS 

Preparation Before Specimen Collection

Collect blood sample for this test after fasting overnight (for 8–12 hours). Fasting means that no food or drink (aside from water) is to be consumed.


Avoid the consumption of any iron-containing supplements for 24 hours prior to collecting blood sample.

Specimen Type

Blood

Volume

50 μL in a microtainer

Container

Microtainer (regular blood tube)

Collection Method

This test requires a blood sample from a finger prick. All supplies for sample collection are provided in the kit.

  1. First wash and dry hands. Warm hands aid in blood collection.
  2. Clean the finger prick site with the alcohol swab and allow to air dry.
  3. Use the provided lancet to puncture the skin in one quick, continuous and deliberate stroke.
  4. Wipe away the first drop of blood.
  5. Massage hand and finger to increase blood flow to the puncture site. Angle arm and hand downwards to facilitate blood collection on the fingertip.
  6. Drip blood into the microtainer tube.
  7. Dispose of all sharps safely and return sample to the laboratory in the provided prepaid return shipping envelope.

NOTES: Avoid squeezing or ‘milking’ the finger excessively. If more blood is required and blood flow stops, perform a second skin puncture on another finger. Do not touch the fingertip.

Specimen Storage

Maintain specimen at temperatures between 2°C and 30°C during storage and transport.

Specimen Stability

Blood samples can be refrigerated or kept at room temperature for up to 7 days.

Causes for Rejection

  • Incorrect or incomplete patient identification
  • Incorrect specimen collection
  • Inappropriate storage and transport conditions
  • Incorrect specimen volume
  • Severe hemolysis

TEST DETAILS

Purpose

To measure iron levels in a blood sample for the evaluation of iron status, including red blood cell production and destruction, iron metabolism, and iron transport.

Increased iron concentrations occur in haemolytic anemias, hemochromatosis, and acute liver disease. Decreased iron concentrations are seen in iron deficiency and anemia of chronic disease, with major causes of iron deficiency including gastrointestinal bleeding and menstrual bleeding.

Limitations

  • This report is not intended for use in medico-legal applications. 
  • These results should be interpreted in conjunction with other laboratory and clinical information.
  • Correct specimen collection and handling is required for optimal assay performance. 
  • Interferences from medication or endogenous substances may affect results.

Methodology

Colorimetric (ferene) (Alinity c Iron assay)

Reference Intervals

  Range (μg/dL)
Male 65 – 175
Female 50 – 170

These reference ranges were obtained from the Alinity c Iron assay package insert. (Source: Tietz NW, editor. Clinical Guide to Laboratory Tests, 4th ed. St. Louis, MO: Elsevier Saunders; 2006:634-635.)