Human Papillomavirus (HPV) High-Risk Test

Introduction

Human papillomavirus (HPV) is a common sexually transmitted DNA virus. Although, most women effectively clear HPV infections within 6 to 12 months, specific HPV genotypes increase the risk of cervical cancer. Any cancers that are associated with HPV are more treatable when diagnosed and treated early; hence the importance of routine screening.

Pricing

$49

How to order a test

Synonyms

• HPV High-Risk Test
• HPV Test for Women

What is Included?

Detection of 14 high-risk HPV genotypes by nucleic acid amplification technology

Turnaround Time

1 – 3 business days
The turnaround time is not guaranteed. The average turnaround time is 1 – 3 business days from the date that the sample arrives at the laboratory. Shipping time for the sample is not included. Additional time is required if the case requires confirmatory or reflex testing, or if the sample is insufficient, or if a recollection is required.

Related Documents

Additional Information and Resources

» Why should I take an HPV test?
» HPV Quick Facts
» What is cervical cancer?
» Are all HPV types associated with an increased risk of cervical cancer?
» Why you should get routine Pap smears

Preparation Before Specimen Collection

• Avoid sexual intercourse for 24 hours and douches 48 – 72 hours prior to sample collection
• Do not collect sample during or shortly after menstrual period

Specimen Type

Cervical swab

Volume

N/A

Minimum Volume

N/A

Container

Cervical specimen container

Collection Method

This test requires a self-collected cervical swab. All supplies for sample collection are provided in this kit.

1. First wash and dry hands, and make sure that you are in a comfortable position with your underwear lowered.
2. Twist the cap and remove the swab from the packaging. Ensure that you do not touch the tip of the swab that is used to collect the sample.
3. Use your free hand to move skin folds at the entrance of your vagina. Carefully insert the swab into your vagina about 2 inches (5 cm) inside the opening of the vagina and gently rotate the swab for 10-30 seconds. This should not hurt, but may feel slightly uncomfortable.
4. Carefully remove the swab and place back into the packaging without touching the tip of the swab that was used for sample collection.
5. Screw the cap back on, and return sample to the laboratory in the provided prepaid return shipping envelope.

Specimen Storage

Maintain specimen at temperatures between 2°C and 30°C during storage and transport.

Specimen Stability

Specimens stored at temperatures between 2°C and 30°C must be tested within 21 days of collection.

Causes for Rejection

• Incorrect or incomplete patient identification
• Incorrect specimen collection
• Inappropriate storage and transport conditions
• Specimen received >21 days after collection

Purpose

To detect nucleic acid from 14 HPV genotypes that are considered high risk for cervical disease. The 14 high-risk genotypes are 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 6.

Limitations

• This report is not intended for use in medico-legal applications.
• These results are intended for screening for high-risk HPV genotypes, and should be interpreted in conjunction with other laboratory and clinical information.
• Correct specimen collection and handling is required for optimal assay performance.
• A negative result does not exclude the possibility of HPV infection, nor does it exclude the possibility of cytologic abnormalities, or of future or underlying cervical cancer.
• The use of this test has not been evaluated for the management of women with prior ablative or excisional therapy, or who are pregnant.

Methodology

Nucleic acid amplification

Reference Intervals

No high-risk HPV genotypes detected